Differential Expression of aA- and aB-Crystallin During Murine Ocular Development
نویسنده
چکیده
Results. During ocular development, aB-crystallin transcripts are present in the lens placode at E9.5. Transcripts of aA-crystallin are first observed in the lens cup at E10 to 10.5. During subsequent development of the lens, aA crystallin transcripts are most abundant in the fiber cells, and aB crystallin mRNA is preferentially expressed in epithelial cells. Transcripts of aAcrystallin were detected only in the lens. In contrast, aB-crystallin transcripts are present in retinal pigment epithelium, optic nerve, extraocular muscle, iris, ciliary body, cornea, and several nonocular sites, such as heart and nasal epithelium.
منابع مشابه
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